Medical Chronobiology Laboratory

Our work in the past decade will meaningfully contribute to an alteration in the perspective of science and substantial improvements in medical practice.

-William J.M. Hrushesky, M.D. 12/28/92

"Corruption wins not more than honesty"

--William Shakespeare Henry VIII, III, ii, 444

Honesty and conidor in all interpersonal relationships is of the highest import. One must be completely honest with oneself and all those with whom one deals directly or indirectly even at the cost of personal popularity or apparent immediate advantage. In order for one's opinion to have weight there must be no doubt that the proposition has been well considered and the conclusion reached without prejudice on the basis of all the information at hand. Likewise, it is clear that one must be anxious to change that conclusion as new information becomes available. While this way of living will not promote one's election to public office, if scrupulously practiced, it will allow one to achieve the respect of one's peers. The respect engendered by this course will promote true friendship regardless of divergence of opinion.

-William J.M. Hrushesky, M.D.

"So long as a man imagines that he cannot do this or that, so long as he determined not to do it: and consequently so long it is possible to him that he should do it."

--Baruch Spinosa Ethics, pt. II proposition 28: Explanation

"Example is not the most important thing in influencing people.. it is the only thing."

"One of the ways of judging a man is deciding whether he is worth the trouble he creates. If he is very productive we can tolerate a ot of trouble. If he is not overly productive, he had better be a nice fellow."

--E.A. Stead, Jr., What This Patient Needs is a Doctor Carolina Press, 1978.



		Progress demands that the inestimable "force" of inertia be underestimated. Thinking "new" thoughts: impossible for most, difficult for all, frightening for many ...and... irresistible for a few. ...dangerous in Science... ...deadly in Medicine... -William J.M. Hrushesky 12/17/95 The Calculus of Life Molecular Biology, like the Cartesian coordinate system, represents space but not time, and without time there is no life. Chronobiology is the first crude attempt toward the calculus necessary to describe and ultimately to understand life. This calculus of life requires the incorporation of non-linear functions, some constrained to periodicity and others more freely resonating at the edge of chaos. -William J.M. Hrushesky, M.D. 7/4/96 Life without Science is Empty; Science without Philosophy is Hollow; Philosophy without Science is a Lie; Life without Philosophy is Dead. -William J.M. Hrushesky, M.D. 9/5/96 "Basically, there's a real difference between filling in the blanks and looking at the world differently. Anyone who doesn't understand the necessity of human nature to resist fundamental realignment of thought doesn't understand human nature." --Quote from Dr. William J.M. Hrushesky The Dallas Morning News January 27, 1992 My goal is happiness. Happiness is achieved by the fulfillment of Nature. Nature in this sense is composed of intellectual, physical, spiritual, and emotional realms. Each individual has a differing capacity within each realm. In order to be happy, we must understand our relative capacity within each realm. One must never fight one's Nature by overfilling one realm and underfilling another. Nature changes constantly and one must flow smoothly between realms as the balance of one's Nature changes. Life may be considered to have stages: preparatory, creative, and advisory. Creativity is of most importance to me currently. This creative stage has been served by a broad preparatory stage in which philosophy, science, and medicine have each been explored. This breadth has fostereda useful peripheral vision. My tools are: a unique perspective, an open and critical mind, and the fact that: "I see no boundaries, only connections." Nature directs me toward changing things for the better. It demands that I influence individuals, and society. -William J.M. Hrushesky, M.D. 1969 - Rephrased 1984 Art is I... Science is we Science increases our power in proportion as it lowers our pride --Claude Bernard Each quantum is linked through the interacting networks of space and time. These fluid glues permeate one another and provide the framework within which objects, emotions, and thoughts are hung. In order to exist within this spatio-temporal relativity, each quantum must be in motion. Each aggregate of quanta, each thing, moves with spatio-temporal coordination. The stability of its path is guaranteed by resonance, resonance across a wide range of frequencies. The dominant frequencies are roughly correlated with the size of the observed aggregate and its neighbors. - -William J.M. Hrushesky, M.D. -WHY IT IS WORTH THE EFFORT- To understand one thing as well as it can be understood is To understand everything a little To understand a second thing as well as it can be understood is To understand everything a little better -CHRONOBIOLOGY HAS THE POWER TO INFLUENCE- The way people think about their bodies The way physicians think about health and disease The way scientists think about living things -William J.M. Hrushesky, M.D. Our work in the past decade will meaningfully contribute to an alteration in the perspective of science and substantial improvements in medical practice. -William J.M. Hrushesky, M.D. 12/28/92 "Corruption wins not more than honesty" --William Shakespeare Henry VIII, III, ii, 444 Honesty and conidor in all interpersonal relationships is of the highest import. One must be completely honest with oneself and all those with whom one deals directly or indirectly even at the cost of personal popularity or apparent immediate advantage. In order for one's opinion to have weight there must be no doubt that the proposition has been well considered and the conclusion reached without prejudice on the basis of all the information at hand. Likewise, it is clear that one must be anxious to change that conclusion as new information becomes available. While this way of living will not promote one's election to public office, if scrupulously practiced, it will allow one to achieve the respect of one's peers. The respect engendered by this course will promote true friendship regardless of divergence of opinion. -William J.M. Hrushesky, M.D. "So long as a man imagines that he cannot do this or that, so long as he determined not to do it: and consequently so long it is possible to him that he should do it." --Baruch Spinosa Ethics, pt. II proposition 28: Explanation "Example is not the most important thing in influencing people.. it is the only thing." "One of the ways of judging a man is deciding whether he is worth the trouble he creates. If he is very productive we can tolerate a ot of trouble. If he is not overly productive, he had better be a nice fellow." --E.A. Stead, Jr., What This Patient Needs is a Doctor Carolina Press, 1978. "We must not overlook the important role that extremists play. They are the gadflies that keep society from being too complacent, or self-satisfied; they are, if sound, the spearhead of progress." --Abraham Flexner (1866-1959)